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Clinical Services

NTL offers numerous testing services, such as  outpatient services and support services at multiple locations throughout Illinois and Indiana. Clinical laboratory and pathology experience, NTL  strives to provide quality and comprehensive services:

  1. Routine and complex analysis of tissue, blood, urine, and other bodily fluids.
  2. Full range of clinical laboratory tests, specimen collection, pap smears and consultative services.
  3. Personal and knowledgeable professionals for general, consultative, educational and technical client support services
  4. Oncology

Certain cytogenetic abnormalities occur in cancers which may provide prognostic implications and assist in therapeutic decision-making. We offer chromosome analysis and FISH testing on bone marrow samples for leukemias and lymphomas. Blood chromosome analysis is available when bone marrow is unattainable and the blast count is greater than 10%. Chromosome analysis and FISH testing on solid tumors is also available.

FISH testing allows for the identification of certain chromosome abnormalities specific to different cancers. FISH is beneficial for detecting abnormalities which may not be visible by traditional chromosome analysis, or may be present at a low level. FISH testing may be ordered individually or as part of a panel specific to the patient’s cancer type.

Prenatal

Chromosome abnormalities may be detected prenatally, which allow the couple to make decisions and plans with as much knowledge as possible. We offer chromosome analysis on both amniotic fluid and CVS. FISH testing for the most common aneuploidies are available for rapid results for both amniotic fluid samples and CVS.

Chromosome abnormalities are a common cause of miscarriage, some of which may be recurrent in a family. Chromosome analysis is available for products of conception. FISH testing for the common aneuploidies can be performed for samples that fail to grow in culture. FISH analysis is also available to confirm triploidy in suspected partial hydatidiform moles.

Constitutional

Blood chromosome analysis is available for conditions such as developmental delay, birth defects, and recurrent miscarriage. FISH testing is also available for the more common micro-deletion syndromes. FISH technology is useful when a specific condition is suspected, particularly when the size of the chromosomal abnormality is below the resolution of karyotyping. Chromosomal microarray is a new technology we offer for detecting chromosome abnormalities at unprecedented resolution, potentially down to the level of a single gene. SNP-based microarray is the highest resolution microarray which interrogates the entire genome for copy number changes for identification of both known and novel genomic disorders.

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